Regardless of team, throwing your stunty players at the enemy team shouldn't be done often really. More often than not it will just lead to you having 1 less player of yours on the field. More of a desperation play than anything else.
For one turn touchdowns / getting down field to steal a loose ball are more worth it for throwing them than aiming to hit opposing players.
But hitting opposing players is fun when it works so if not worried at all about winning then go ahead!